This study was conducted to evaluate the effect of biofertilizers, livestock and chemical fertilizers and corm weight on yield and yield components of saffron in Mehvalat city in the 2011-2011 crop year in a factorial split plot design with four replications in which chemical fertilizers and livestock At three levels (100%, 50% and no use of livestock and chemical fertilizers) as the main plot factor and sub-plot factor including: Factorial composition of biological fertilizer was considered at three levels (nitroxin fertilizer, biosporphosphate and without fertilizer) and corm size at three levels (corms weighing 4 to 6, 8 to 10 and 12 to 14 g). The results of the first year of the experiment showed that the effect of animal manure and chemical fertilizer on fresh saffron flower weight, stigma and cream length and number of flowers per unit area was significant and with increasing fertilizer application levels, their amount increased. Also, with increasing the size of saffron mastic, the weight of fresh flowers, the number of flowers per unit area and the length of stigma and cream increased significantly. The study of the effect of biological fertilizers on saffron cultivation showed that the highest number of flowers per unit area (average 5.4 flowers per square meter) was obtained from the treatment of nitroxin, biosphere phosphate and non-biological fertilizers, respectively. The use of nitroxin fertilizer increased the fresh weight of flowers by 27.8%; While the use of biosphere fertilizer did not have a significant effect on the amount of this trait. The length of saffron stigma and cream was not affected by the use of biological fertilizers.